摘要
通过考察C18 硅胶吸附分离中液固两相间的物质传递 ,建立了紫杉醇在该吸附柱上分离的速率模型 ,并用有限元方法对模型进行了求解 ,模型计算值与实验值吻合良好。研究体积超载和浓度超载两种方式对紫杉醇吸附分离过程的影响说明 ,在紫杉醇的C18 硅胶吸附制备中 。
The kinetic model for the adsorption process to separate taxol by C 18-silica gel has been established through analysis of the basic transport phenomena between solid phase and liquid phase. Elution curves were obtained through numerical solution of the partial differential equations by finite element method. The numerical solution of model agreed well with experimental data. The calculation demonstrated that, in the adsorption process of taxol preparation, the capacity of taxol on the C 18-silica gel column could be increased by volume overload and concentration overload, with the better result for concentration overload.
出处
《化学工程》
CAS
CSCD
北大核心
2002年第5期1-10,共10页
Chemical Engineering(China)
基金
国家自然科学基金重点项目 ( 2 9736 180 )
