新生儿危重症伴抗利尿激素异常分泌综合征的相关因素分析

Related factor analysis of neonatal high-risk disease with SIADH

目的 探讨新生儿危重症伴抗利尿激素异常分泌综合征 (SIADH)的相关因素。方法 对 16 4例危重新生儿通过监测血钠及血渗透浓度 ,尿钠及尿渗透浓度判断是否存在SIADH ,用Logistic回归方法找出引起新生儿SIADH的相关因素。结果 颅内疾患、肺部疾患和不适当的液体输入是引起新生儿危重症SIADH的危险因素。结论 危重新生儿易发生SIADH ,增加救治难度 ,适当控制危重新生儿液体入量可有效地控制SIADH的发生。

Objective To explore the related factors of neonatal high-risk disease with SIADH.Methods 164 high-risk newborns were enrolled in this study, serum sodium and osmolality as well as urine sodium and osmolality were monitored to judge whether they suffered from SIADH or not.The related factors which can canse neonatal SIADH were found by Logistic regress method.Results Intracranial disorders, pulmonary disorders and inappropriate fluid infusion were the high-risk factors which can cause neonatal SIADH.Conclusion High-risk newborns are likely to suffer from SIADH,which will increase the difficulty to cure the underlying disorders.Appropriate fluid restriction of high-risk newborns can effectively decrease the attack of SIADH.