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人工心脏瓣膜置换术后大出血停用华法令治疗的安全性及期限 被引量:2

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摘要 目的 探讨人工心脏瓣膜置换术后因大出血停用华法令期限和血栓栓塞的危险。方法  11例换瓣术后患者因大出血全部停用华法令住院病人 ,2例自行恢复 ,7例给维生素K ,其中 1例同时输注新鲜冰冻血浆 ,4例输注红细胞。停止抗凝时间 4~ 2 0d。结果 所有停用华法令者无出现血栓栓塞并发症 ,1例颅内出血院内死亡。余10例病人重新开始调整接受华法令治疗 ,随访 3个月有 2例出现消化道出血。结论 人工心脏瓣膜置换术后因大出血住院停用华法令血栓栓塞的危险性低 ,恢复华法令治疗有复发少量出血 ,国人应加强门诊抗凝随访。
作者 刘戎 刘峰
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2002年第12期737-737,745,共2页 Chinese Journal of Practical Internal Medicine
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参考文献5

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同被引文献11

  • 1李永胜,沈迎念,万磊,熊杰,李树生,郑智.口服华法令抗凝致出血的原因分析[J].内科急危重症杂志,2006,12(1):18-19. 被引量:15
  • 2徐玮,沈宏.重型颅脑损伤后凝血功能变化的研究[J].浙江创伤外科,2007,12(2):98-101. 被引量:11
  • 3陈新谦 金有豫 汤光.新编药物学[M]15版[M].北京:人民卫生出版社,2003.583.
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  • 6Cannageiter S C, Rosendaal F R, Wintzen A R, et al. Optimal oral anticoagulant therapy in patients with mechanical heart valves[J]. N Engl J Med, 1995, 333(1): 11-17.
  • 7Cohen DB, Rinker C, Wilberger JE. Trau- matic brain injury in anticoagulated pa- tients[J]. J Trauma, 2006, 60: 553-557.
  • 8Lavoie A, Ratte S, Clas D, et al. Preinjury warfrin use among elderly patients with closed head injurys in a trauma center[J]. J Trauma, 2004, 56: 802-807.
  • 9Pieracci FM, Eachempati SR, Shou J, et al. Degree of anticoagulation, but not warfarin use itself, predicts adverse outcomes after traumatic brain injury in elderly trauma pa- tients[J]. J Trauma, 2007, 63: 525-530.
  • 10Wesley D. McMillian, et al. Management of prehospital antiplatelet and anticoagulant therapy in traumatic head injury: a review [J]. J Trauma, 2009, 66: 942-950.

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