摘要
Objective Percutaneous coronary intervention(PCI) in unstable angina pectoris has been shown to have a favorable outcome with relatively low mortality. Despite this, risk factors that predict mortality in such patients are continuing to be refined. This study aimed to further clarify these perdictors of mortality. Methods A retrospective analysis of patient characteristics, routinely collected at the time of PCI (April 1998 to January 2001) , on 109 consecutive patients was undertaken. Univariate analysis of clinical and anatomical parameters thought to affect outcome following PCI was performed. Those found to be significant were entered in a multiple logistic regression model to identify which are independent predictors of early(≤30 day) and late ( 1 year ) mortality. Patients were evaluated in 4 age groups as follows: A<55(mean 45.2), n=20; B 55-64(mean 57.9), n=32; C 65-74 (mean 68.5), n=32; and D >75 (mean 78.2), n=25. Results The cohort mortality was 6.4%(n=7), and there was a marked increase death with age; A, 0%(n=0); B, 0%(n=0); C 6.3%(n=2); and D, 20%(n=5). Early mortality was highest in group D (3/25=12%) compared to grpup A, B and C ( 0, 0 and 3.1%, respectively). Multivariate analysis comfirmed that comorbidity( p=0.007), diabetes mellitus ( p=0.052), left ventricular ejection fraction<50%(p=0.021), and age (p=0.0005) were all significant independent predictors of mortality. However, only age was found to be an independent predictor of early death(P=0.009). Conclusions Although comorbidity, diabetes mellitus and left ventricular dysfunction are predictors of mortality in patients undergoing percutaneous coronary intervention for unstable angina up to 1 year, only age is a significant independent predictor of both early and late death.
Objective Percutaneous coronary intervention(PCI) in unstable angina pectoris has been shown to have a favorable outcome with relatively low mortality. Despite this, risk factors that predict mortality in such patients are continuing to be refined. This study aimed to further clarify these perdictors of mortality. Methods A retrospective analysis of patient characteristics, routinely collected at the time of PCI (April 1998 to January 2001) , on 109 consecutive patients was undertaken. Univariate analysis of clinical and anatomical parameters thought to affect outcome following PCI was performed. Those found to be significant were entered in a multiple logistic regression model to identify which are independent predictors of early(≤30 day) and late ( 1 year ) mortality. Patients were evaluated in 4 age groups as follows: A<55(mean 45.2), n=20; B 55-64(mean 57.9), n=32; C 65-74 (mean 68.5), n=32; and D >75 (mean 78.2), n=25. Results The cohort mortality was 6.4%(n=7), and there was a marked increase death with age; A, 0%(n=0); B, 0%(n=0); C 6.3%(n=2); and D, 20%(n=5). Early mortality was highest in group D (3/25=12%) compared to grpup A, B and C ( 0, 0 and 3.1%, respectively). Multivariate analysis comfirmed that comorbidity( p=0.007), diabetes mellitus ( p=0.052), left ventricular ejection fraction<50%(p=0.021), and age (p=0.0005) were all significant independent predictors of mortality. However, only age was found to be an independent predictor of early death(P=0.009). Conclusions Although comorbidity, diabetes mellitus and left ventricular dysfunction are predictors of mortality in patients undergoing percutaneous coronary intervention for unstable angina up to 1 year, only age is a significant independent predictor of both early and late death.
出处
《海南医学》
CAS
2002年第12期155-155,共1页
Hainan Medical Journal
