流行性腮腺炎病毒性脑膜炎短程高效治疗临床观察

Clinical studies on the short-course and efficient treatment of mumps meningitis

目的 探讨流行性腮腺炎病毒性脑膜炎 (腮脑 )短程高效的治疗方法。方法 以临床和实验室确诊的 15 5例腮脑患者为观察组 ,采用地塞米松一次性鞘内注射治疗方法 ,并与同期入院的常规对症治疗组对照。结果 观察组退热时间、头痛和脑膜刺激症状消失时间及治愈时间分别是 32h、15h、12h、3.1d ,明显优于对照组的 5 8h、2 4h、32h、6 .5d ,且差异有非常显著性或差异有显著性 (P <0 0 1或0 0 5 )。结论 地塞米松一次性鞘内注射疗法治疗腮脑短程、高效 ,安全。

Objective To investigate the short course and efficient way to treat mumps meningitis. Methods Totally 155 cases of mumps meningitis treated by intrathecal injection with dexamethasone only once were enrolled as experimental group and 55 similar cases treated with the common therapy as control. Results The time for recoveries of temperature, headache, the pathologic reflexes and the total time of treatment were 32 hours, 15 hours, 12 hours and 3.1 days,respectively, while those of the control group were 58 hours, 24 hours, 32 hours, 6.5 days respectively. There was statistical difference between the two groups ( P <0.01 or 0.05). Conclusion Intrathecal injection with dexamethasone only once is efficient and safe in the treatment of mumps meningitis.