摘要
目的 :探讨乙型肝炎病毒 (HBV)携带者发生垂直传播的同时并未发生夫妻间水平传播的可能原因。方法 :以已确定传播 HBV给子代的 10名女性携带者与 8名男性携带者的配偶为研究对象 ,以 1∶ 2的原则选配对照 ,检测病例与对照组的 Ig G、Ig A、Ig M、C3、C4与抗 - HBs。结论 :研究对象未检出抗 - HBs,对照组阳性率 4 8.0 %。与对照组比较女性携带者配偶 Ig G、C3、C4偏低 ,男性携带者配偶 C3、C4偏低。结论 :携带者配偶未发生 HBV感染的原因可能是存在免疫耐受 。
Objective:To study the cause by which HBV carriers transmitted HBV to their foetus,but did not transmit HBV to the spouse.Methods:The spouses of 10 female and 8 men carriers were matched with control.IgG,IgA,IgM,C3,C4 and anti HBs were detected in the groups.Results:Anti HBs of the spouses of HBV carriers was negative,while that of controls was 48 0% positive.IgG?C3?C4 of the spouses of female carriers and C3?C4 of the spouses of men carries were lower than those of the control.Conclusion:Immunological tolerance may be the cause by which the spouses of HBV carriers were not infected.The immunological tolerance was relation to immunological quality of the person.
出处
《现代预防医学》
CAS
2002年第6期780-781,共2页
Modern Preventive Medicine
关键词
乙型肝炎病毒
传播
免疫耐受
Hepatitis B virus
Transmission
Immunological tolerance
