非酮症糖尿病癫痫临床分析

A clinical analysis of epilepsy in non-ketotic hyperglycaemia

目的：探讨非酮症糖尿病性癫痫的临床规律，提高早期诊断率。方法：对20例非酮症糖尿病性癫痫的临床资料进行回顾性分析。结果：12例糖尿病性患者在血糖控制不理想状态下发生癫痫，8例患者以癫痫作为糖尿病的首发症状。15例表现为部分运动性发作，占75%。应用胰岛素积极控制血糖是主要治疗措施，避免应用苯妥英钠。结论：提高对本病的认识，早期诊断，降低血糖是控制癫痫发作的关键。

Objective: To discover the clinical characteristics of epilepsy in non-ketotic hyperglycaemia and improve the diagnostic accuracy in early stage. Methods: The clinical data of 20 patients with epilepsy in non-ketotic hyperglycaemia were studied retrospectively. Results: Twelve patients had recurrent episodes of seizure when glycaemic control was lost. In eight cases diabetes mellitus was a new diagnosis. Glycemic levels varied from 17.2 to 31.1 mmol/L. Fifteen patients with focal seizures accounted for 75%. Seizure control occurred after insulin treatment, no patients benefited with phenytoin. Conclusion:It is important to increase the knowledgc of epilepsy in non-ketotic hyperglycaemia and early diagnose and insulin treatment are essential in controlling seizures.