老年糖尿病住院患者降糖药物治疗方式分析与疗效评价

Analysis of Hypoglycemic Drug Treatment Pattern and Evaluation of Curative Effect in Elderly Diabetic Inpatients

目的 :为促进临床合理用药 ,对 2 92例老年糖尿病住院患者的降糖药物治疗方式及其影响因素进行分析研究并评价其疗效。方法 :采用回顾性调查方法对老年糖尿病住院病历的相关内容进行统计分析。疗效指标参照WHO推荐的标准。结果 :随病程延长口服降糖药治疗者明显减少 ,胰岛素应用比例逐渐增加 ,但总体胰岛素使用率较低 ;入院时HbA1c控制良好和一般的患者住院时采用口服降糖药治疗较多 ,而HbA1c控制不良者则较多采用胰岛素治疗 ;老年糖尿病应用胰岛素的首要原因是控制高血糖 ;临床口服降糖药存在不合理应用情况 ;胰岛素治疗组疗效显著优于口服降糖药治疗组。结论 :对于老年糖尿病患者经口服降糖药治疗后病情仍然控制不良者 ,应及时采用或加用胰岛素治疗 ,并加强口服降糖药的合理使用 。

To analyze the hypoglycemic drugs treatment pattern and evaluate the curative effect in 292 inpatients with elderly diabetes. Method: The concerned content of elderly diabetic inpatients were statistically analyzed by retrospective investigation. The index of curative effect referred to WHO standard. Reuslt: With the prolongation of course, inpatients receiving the therapy of oral antidiabetic drugs were significantly decreased, inpatients receiving insulin were gradually increased, but the overall using ratio of insulin was lower. The most of inpatients with good and general control of HbA 1c on admission to hospital took oral antidiabetic drugs. while those with bad HbA 1c control took insulin. The chief aim of insulin therapy was to control hyperglycemia. We also found some unreasonable administration of oral antidiabetic drugs. To curative effect, insuin was sifnificantly good to oral antidiabetic drugs. Conclusion: In order to obtain better therapeutic effect, we suggest that the elderly diabetic patients with poor blood sugar control by oral antidiabetic durgs should be given insulin timely, meanwhile we should strengthen the clinically rational use of oral antidiabetic drugs.