隆突性皮肤纤维肉瘤的综合治疗

The combined therapy of dermatofibrosarcoma protuberans.

目的 探讨隆突性皮肤纤维肉瘤的临床特点、治疗方式及影响预后的因素。方法 回顾性分析我院近 10年收治的 2 8例隆突性皮肤纤维肉瘤患者 ,均行肿块局部扩大切除 ,术后两周行6 0 Go -r线放疗。结果 本组 2 8例均行手术及放疗 ,随访 5～ 9年 ,术后复发率为 2 8 6% (8 2 8) ;3年、5年生存率分别为96 4% (2 7 2 8)、92 9% (2 6 2 8)。结论 隆突性皮肤纤维肉瘤是一种低恶性肿瘤 ,行肿块局部扩大切除 ,术后辅助放疗可有效地降低复发率 ,对提高生存率及生存质量均有积极作用 。

Objective To explore the clinical features, treatment and the prognostic factors for dermatofibrosarcoma protuberans.Methods Twenty eight cases of dermatofibrosarcoma protuberans were analyzed in our hospital from 1987 to 1997. All cases were performed extensive lumpectomy and radiotherapy two weeks later. Results The patients were followed up for 5 to 9 years. The rate of recurrance was 28.6%(8/28). The 3～,5～year survival rates were 96.4%(27/28). 92.7%(26/28). Conclusion Dermatofibrosarcoma protuberans is a maligant tumor with low malignancy. Extensive lumpectomy and radiotherapy can decrease its rate of recurrance. It is an effective treatmeat in improving survival rate and survival quality of dermatofibrosarcoma protuberans. It is the best treatment for dermatofibrosarcoma protuberans.