北刘寄奴中奎尼酸酯类化学成分研究

Quinic Acid Esters from Herba of Siphonostegia chinensis

目的:对中药北刘寄奴中奎尼酸酯类活性成分进行化学研究。方法:溶剂提取及各种柱色谱法分离,光谱技术鉴定结构。结果:从北刘寄奴中分离得到3个奎尼酸酯类化合物,分别为3,十二咖啡酰基奎尼酸(I),灰毡毛忍冬素F(Ⅱ),3,4,5-三咖啡酰基奎尼酸甲酯(Ⅲ)。结论:均为首次从该属植物中分离得到。

Objective: To study the bioactive constituents, quinic acid esters, from Siphonostegia chinensis. Method: The compounds were extracted with solvents, isolated by various column chromatography and identified by spectroscopic methods. Result: Three quinic acid esters were isolated and identified as 3,4-di-O-caffeoylquinic acid(I), macranthoin F(Ⅱ), and methyl ester of 3, 4,5-tri-O-caffeoylquinic acid (Ⅲ). Conclusion: All compounds were isolated from Siphonostegia for the first time.