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高血压病对左室功能影响的临床研究 被引量:1

Evaluation of left ventricular function in patients with hypertension
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摘要 目的:应用声学定量(AQ)技术评价不同左室几何构型高血压(EH)患者的左室收缩和舒张功能。方法:对51例EH患者和20例正常对照进行了AQ检测,根据左室重量指数和相对室壁厚度,EH组又分为左室几何构型正常组、左室向心性重构组和左室向心性肥厚组。结果:左室几何构型正常组左室舒张功能无明显变化,而左室容量负荷出现增大,进一步引起早期左室泵功能的增强;向心性重构组患者被动充盈减弱,主动充盈增强,左室舒张功能明显减退;左室向心性肥厚型者随着左室肥厚的发展,左室收缩和舒张功能均显著减退。结论:EH患者左室几何构型对心功能产生不同的影响,应对症治疗。 Objective:To evaluate left ventricular systolic and diastolic function in patients with hypertension by acoustic quantification(AQ)technique.Methods:51patients with hypertension and20control subjects were studied by AQ technique.The hypertension group was divided into three sub-groups by left ventricular mass index and relative wall thickness:normal left ventricular geometry,con-centric remolding and concentric hypertrophy subgroup.Results:Compared with control subjects,pa-tients in normal left ventricular geometry subgroup had normal left ventricular diastolic function,but left ventricular systolic function increased.Left ventricular diastolic function significantly decreased in patients of concentric remolding subgroup,but diastolic function was normal.Both left ventricular diastolic and systolic functions were greatly lower in patients of concentric hypertrophy subgroup.Conclusion:Patients with difference geometry hypertension had different left ventricular function.
出处 《山东大学学报(医学版)》 CAS 2002年第6期523-525,共3页 Journal of Shandong University:Health Sciences
基金 山东省科委科研基金资助课题(981216509)
关键词 高血压 左室功能 临床研究 Hypertension ventricular function,Left Geometric remodeling
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  • 2吴晓霞,智光,孙琪,阎国辉,周肖,徐勇.正常成人心肌应变及应变率的速度向量成像定量分析[J].临床超声医学杂志,2007,9(2):76-78. 被引量:25
  • 3中国高血压防治指南修订委员会.中国高血压防治指南.高血压杂志,2005,13(1):2-41.
  • 4Artis NJ,Oxborough DL,Williams G,et al.Two-dimensionalstrain imaging:A new echocardiographic advance with researchand clinical applications.Int J Cardiol,2008,123(3):240-248.
  • 5Gradman AH,Alfayoumi F.From left ventricular hypertrophy tocongestive heart failure:Management of hypertensive heart dis-ease.Prog Cardiovasc Dis,2006,48(5):326-341.
  • 6Burgess MI,Jenkins C,Sharman JE,et al.Diastolic stress echo-cardiography:Hemodynamic validation and clinical significance ofestimation of ventricular filling pressure with exercise.J Am CollCardiol,2006,47(9):1891-1900.
  • 7Pavlopoulos H,Grapsa J,Stefanadi E,et al.The evolution ofdiastolic dysfunction in the hypertensive disease.Eur J Echocar-diogr,2008,9(6):772-778.
  • 8Mizuguchi Y,Oishi Y,Miyoshi H,et al.Concentric left ven-tricular hypertrophy brings deterioration of systolic longitudinal,circumferential,and radial myocardial deformation in hyperten-sive patients with preserved left ventricular pump function.JCardiol,2010,55(1):23-33.
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