慢性肝炎患者血清甘胆酸与其肝组织炎症的相关性

A Study on the Correlation between the Serum GA Level and the Liver Tissue Inflammation Activity in Chronic Hepatitis Pa- tients

目的:探讨慢性肝炎患者血清甘胆酸(GA)与其肝组织炎症病理分度(G)的相关性。方法:随机选择100例慢性肝炎患者,抽静脉血检测其血清甘胆酸,肝组织活检,病理检查。结果:肝组织炎症活动度越高,血清甘胆酸升高愈明显,G_1与G_2,_2与G_3,G_3与G_4之间比较,呈现显著差异(P<0.05),G与血清GA两者有相关性(r=0.892)。结论:血清甘胆酸是观察慢性肝炎患者肝组织炎症变化的较敏感而准确的指标。

Objective: To study the correlation between the serum GA level and the liver tissues inflammation activity in chronic hepatitis patients. Methods: 50 patients with chronic hepatitis were randomly selected and their serum GA was tested and the liver tissue inflammation activity was examined with pathological methods. Results: As the liver tissues inflammation activity was elevated, the serum GA level went up (P < 0. 05). The serum GA level was more correlated with the liver tissue inflammation activity (G) in chronic hepatitis B patients. (r = 0. 892). Conclusion: Serum GA is a sensitive parameter for examining the liver tissue inflammation activity of the patients with chronic hepatitis.