图形翻转视觉诱发电位在视觉通路肿瘤中的应用

The diagnostic value of the pattern reversal visual evoked potentials in patients with brain tumors along the visual pathways

目的 探讨图形翻转视觉诱发电位 (patternreversalvisualevokedpotentials ,PRVEP)在视觉通路脑肿瘤诊断中的应用价值。方法 对 83例经CT和 /或MRI证实为视觉通路脑肿瘤的患者和 2 0例正常人进行PRVEP检查。其中 2 4例患者 48只眼同时行眼科全自动视野计检查。结果 患病组和对照组之间PRVEPP10 0波潜伏期和波幅明显不同 ,视觉通路上不同部位的脑肿瘤有不同的PRVEP特征表现 ,PRVEP的变化类型与视野之间密切相关。结论 PRVEP监测能灵敏反映病变对视觉通路的损害 ,并有助于视路脑肿瘤的早期诊断、定位及视觉功能状态的评价 。

Objective To explore the diagnostic value of pattern reversal visual evoked potentials(PRVEP) in patients with brain tumors along the visual pathways. Methods Twenty healthy volunteers and 83 patients with proven brain tumors were tested with PRVEP. The visual field of both eyes in 24 of 83 patients were tested by use of perimetry. Results P100 peak latency and amplitude are statistically significantly different between groups of patients and normal controls. The characteristics of PRVEP are closely related to the locality of brain tumors along the visual pathways and the visual field deficits. Conclusion PRVEP is sensitive in revealing compression on visual pathways. It is helpful to the early diagnosis and detection of localized brain tumors and the assessment of the functional status of visual pathways.