后程立体定向放射治疗体部恶性肿瘤

Late Course Stereotactic Radiotherapy for 80 Patients With Body Malignancies

目的 :探讨后程立体定向放射治疗对体部恶性肿瘤的治疗价值。方法 :选择 80例体部恶性肿瘤 ,包括原发癌 6 3例 ,转移癌 17例。先给予常规外照射DT4 0～ 5 0Gy 4～ 5W ,休息 7～ 10d后 ,行后程立体定向放射治疗补量治疗 ,分次治疗方法为DT4～ 8Gy F ,隔日 1次 ,4～ 6次为 1个疗程 ,平均补量为DT30Gy(2 4～ 4 0Gy)。结果 :治疗后 3～ 6个月 ,CT及MRI复查示 :6 3例原发癌中 ,5 5例肿瘤缩小或消失 ,占 87% ;17例转移癌中有 14例肿块明显缩小 ,占 82 %。 73例患者KPS评分有提高 ,占91%。全部病例均未出现明显放疗并发症。结论 :立体定向放射治疗体部恶性肿瘤疗效肯定 ,后程立体定向放射治疗结合常规放疗对于改善患者预后是有益的。

Objective To explore the therapeutic value of late course stereotactic radiotherapy in the treatment of body malignancies.Methods 80 patients with body malignancies including 17 metastatic and 63 primary were chosen to study.All patients were undertaken late course stereotactic radiotherapy after the routine radiation 7 to 10 days.The stereotactic mean dose was 30 Gy.All patients were followed up 3 to 12 months.Results After the stereotactic radiotherapy 3-6 months,55 of 63 primary tumor were reduced,14 of 17 metastatic tumor were reduced.KPS was improved in 73 of 80 patients.All patients had no radiation complications.Conclusions The stereotactic radiotherapy for body malignancies was effective.Late stereotactic radiotherapy combination general radiotherapy were favourable in improving prognosis.