北京地区肠道致病菌的分布及耐药状况

Distribution and resistance of enteric pathogenic bacteria in Beijing area

目的 监测北京地区肠道致病菌的组成及耐药状况 ,为本地区的流行病学研究及临床合理用药提供依据。方法 通过常规大便培养 ,筛选出致病菌后经生化及血清学进一步鉴定到种、群或血清型。结果 肠道病原菌感染 ,以男性为主 ,儿童和青年发病为多 ,6、7月为腹泻发病高峰。病原以志贺菌属居首位 ,其次是弧菌。各菌属对抗生素的敏感率有差异。结论 北京地区感染性腹泻的病原种类繁多 ,有性别、年龄、季节的分布特点 ,耐药性不同 。

Objective To monitor the distribution and resistance of enteric pathogenic bacteria in Beijing area to offer the data for guiding epidemiologic study and clinical treatment. Methods Enteric pathogenic bacteria were cultured and identified to spicies, group, and serotype with the biochemical and serologic test. Then, the susceptibility of bacterium to antimicrobial agents were tested. Results Enteric pathogenic bacteria infection occurred with male, children, and youth being prominant. It peaked in June and July. Shigellae spp and Vibrio spp were the main pathogenic bacteria of intestinal tract. There presented difference among the sensitive rates of differential spicies, or groups to antimicrobial agents. Conclusions There are many spicies of enteric pathogenic bacteria causing infective diarrhea in Beijing area. Their distributions are different in sex, age and season. The is resistance rate are different needing surveillance.