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异丙酚清醒镇静用于眼科手术的临床观察 被引量:2

Clinical observation on the conscious sedation effect of disoprofol in ophthalmologic operation
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摘要 目的 观察异丙酚清醒镇静用于眼科手术的镇静效果及对眼压的影响。方法 选择成年眼科手术患者2 0例 ,随机均分为两组 :A组 (清醒镇静组 )和 B组 (对照组 )。术前 5 min,A组用微泵按比例 1 0 0μg· kg-1·min-1的速率快速输注 5 min,而后改为 1 0~ 1 5μg· kg-1· min-1维持 ;B组肌注氟芬合剂 2 m L。观察两组的镇静状态与合作评分及对眼压的影响。结果  A组的镇静评分较 B组有显著性差异 (P <0 .0 5 ) ;合作评分较 B组有非常显著性差异 (P <0 .0 1 )。A组异丙酚快速输注后 ,眼压下降显著 ,并能维持在较低水平 ;B组肌注氟芬合剂后 ,眼压无显著性变化。结论 眼科手术中应用异丙酚清醒镇静 ,可获得安全有效的镇静效果 ,能使眼压显著下降 。
出处 《西北药学杂志》 CAS 2002年第6期265-266,共2页 Northwest Pharmaceutical Journal
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