甲状旁腺功能减退症头颅CT表现

CT findings of brain in patients with hypoparathyroidism

目的进一步认识甲状旁腺功能减退症的头颅CT特征,以提高CT诊断的准确性。方法回顾分析16例临床确诊甲状旁腺功能减退症的临床、实验室检查及CT资料,其中继发性7例,特发性9例,均行CT平扫。结果16例均显示脑实质钙化。苍白球钙化见于16例、尾状核头钙化16例尾状核体钙化10例、豆状核钙化13例、壳核钙化12例、齿状核钙化12例、丘脑钙化8例,顶叶钙化11例、额叶钙化10例、枕叶钙化8例、颞叶钙化4例,钙化基本呈双侧对称性。结论甲状旁腺功能减退症CT表现具有一定特征性,CT对病变程度的判定有一定价值,但明确定性则需结合临床特征及实验室检查。

Objective To understand the CT features of the b rain in patients with hypoparathyro idism so as to elevate the diagnostic accuracy.Methods Sixteen patients with clinically pr oved hypoparathyroidism(seven cases of secondary-and nine ca ses of idiopathic hypoparathyroidism)underwent CT plain scans.Clinical,laboratory data and CT features of al l patients were retrospectively ana-lyzed.Results On CT images of the brain,these paien ts were noted to have variable degree of calcification in different parts of brain parenchyma i.e,globus pallidus(16cases).head and body of caudate nucleus(16and 10cases),lentiform nucleus(13cases),putamen(12cases),dentate nucleus(12cases),thalamus(18cases),parietal lobe(11cases),frontal lobe(10cases).occipital lobe(8cases),and temporal lobe(4cases).The calcified lesions seen in brain parenchyma were basically presente d with bilateral symmetry.Conclusion CT findings of the brain in patients wit h hypoparathyroidism have certain c haracteristics those are helpful to identify the extent and /or the location of the lesions but the quali ta tive diagnosis of this disease sti ll needs the combination with clinic al manifestations and laboratory tests.[