二尖瓣返流对扩张型心肌病患者的左室充盈模式的影响

The impact of mitral regurgitation on left ventricular filling pattern in patients with dilated cardiomyopathy

目的 :探讨二尖瓣返流对扩张型心肌病 (DCM)患者左室充盈的影响。方法 :对 30例有轻度二尖瓣返流的DCM患者和 30例二尖瓣返流较重的DCM患者与 30例正常人的舒张期二尖瓣口血流超声心动图检查结果进行分析。结果 :反映左室舒张功能的二尖瓣血流频谱早期充盈峰速度 (VE)、晚期充盈峰速度 (VA)、VE/VA等参数在轻微二尖瓣返流组与对照组比较有明显差异 (P <0 .0 0 0 1) ,而严重二尖瓣返流组上述参数与对照组相比却无显著差异 (P >0 .0 5 )。结论 :超声心动图二尖瓣口血流指标显示二尖瓣返流轻微的DCM患者左室主动充盈减弱 ,被动充盈相对增加 ,而对二尖瓣返流较重的DCM患者的VE/VA却表现为假性正常化。

Objective:To explore the impact on left ventricular filling pattern which decided by the extent of mitral reflow in dilated cardiomyopathy(DCM) individuals.Methods:5'BZWe contrasted the transmitral inflow velocity detected by echocardiography in three groups:DCM patients with mild mitral reflow(DCM-mild-MR,n=30),DCM patients with serious mitral reflow(DCM-serious-MR,n=30) and ordinary people (OP,n=30).5'HZResults:The peak E velocity(VE),peak A(VA) velocity and VE/VA were significantly different between DCM-mild-MR and OP group(P<0.0001),while there are no difference between DCM-serious-MR and OP group(P>0.05).Conclusion:Derived the transmitral inflow velocity detected by echocardiography,left ventricular initiative filling of the DCM-mild-MR individuals were weakened,at the same time left ventricular passive filling were enhanced but the DCM-serious-MR individuals behaved as artificial normalization.