糖尿病性视网膜病变的视网膜电图改变

The Abnormal Elextroretinogram in Diabetic Retinopathy

本文报告了67例(124眼)糖尿病患者及50名(75眼)健康者的视网膜电图(ERG)检查结果。糖尿病患者ERG的a,b波振幅降低,峰时延迟和振荡电位(OPs)消失均随着视网膜病变程度的加重而依次增高(P<0.01)。有玻璃体出血史的患眼较无出血眼振幅降低率高(P<0.05)。晶体明显混浊眼也此轻度混浊或不混浊眼振幅降低率高((P<0.01.)。结果提示:ERG所反映的视网膜功能状况与视网膜病变程度密切相关。病变严重的,视功能损害也显著。未见视网膜病变时,也可能出现振幅降低和OPs消失。

The dark-adapted efectroretinogram (ERG) was investigated in 67 diabetic patients (124 eyes) and in 50 normal subjects (75 eyes). The results showed that the rate of reduced amplitudes and lengthened peak times of a, b waves, as well as the rate of extingaished oscillatory potentials in diabetics ERG were elevated in sequence from no, mild, moderate to severe retinopathy (P<0.01). The rate of reduced amplitudes was higher in eyes with vitreous hemorrhage than those without hemorrhage (P<0.05); and the above stated rate was positively related to the degree of lens opacity (P<0.01). The retina function represented by ERG was greatly related to the severity of diabetic retinopathy, and it was damaged seriously while diabetic retinopathy was severe. It was also found that the amplitudes of a, b waves could be reduced and oscillatory potentials could be extinguished in some diabetic patients without retinopathy. The effects of tens opacity and vitreous hemorrhage upon the results of ERG is also discussed