异种胶原生物膜鼓膜成形术实验研究

Experimental Study of Exogenous Collagen Membrane in Myringoplasty

家兔10只(20耳),切除全部鼓膜,以异种胶原生物膜作鼓膜移植术。术后10、20、40、60日观察鼓膜愈合情况。结果19耳移植成功。同时观察移植前后组织学和超微结构形态,证实该移植材料具有良好的生物相容性,是一种富有实用价值的鼓膜移植材料。

Myringoplasty using exogenous collagen membrane was carried out in 10 rabbits (20 ears) after complete removal of drumhead. The healing results were observed at 10, 20, 40, and 60 d, after operation. The 19 ears were transplanted successfully. Meanwhile, observational comparisons were made of the histology and ultrastructural morphology of the rabbits tympanic membrane before and after transplantation. The results confirmed that the graft has a good property of biocompatibility.and that it is of great practical value in the transplantation of tympanic membrane.