摘要
目的分析中国成人HIV/AIDS临床症状与周围血CD_4^+细胞数之间的关系。方法对1990年-2001年在本院就诊的160例成人HIV/AIDS CD_4^+、CD_8^+及临床症状进行跟踪分析。结果①共检测CD_4^+、CD_8^+ 516例次:CD_4^+≥200/μl 278例次(53.9％),CD_4^+<200/μl 238例次(46.1％);②在CD_4^+≥200/μl的278例次中,临床症状表现为乏力66例次(23.7％),记忆力下降51例次(18.3％),脱发65例次(23.4％),体征中表现为淋巴结肿大128例(46.3％),出现带状疱疹65例次(23.3％);CD_4^+<200/μl的238例次中,临床症状表现为发热228例次(95.8％),腹泻216例次(90.8％),口腔霉菌感染合并口腔溃疡192例次(80.7％),皮疹67例次(28.2％),体重下降168例次(70.6％)。结论中国成人HIV/AIDS患者在CD_4^+≥200/μl时临床症状较少,主要表现为乏力、脱发、记忆力下降等非特异性症状,体征主要表现为淋巴结肿大;CD_4^+<200/μl时临床症状集中表现为发热、腹泻、口腔霉菌感染合并口腔溃疡、体重下降等。
Objective To investigate the relationship between clinical manifestation and change in CD_4^+ lymphocyte count in
HIV/AIDS patients. Methods The clinical data of 160 HIV/AIDS patients who came to consult in our hospital during 1999 - 2001 were
retrospectively analyzed. Results ① In all the patients, CD_4^+ and CD_8^+ lymphocyte count was performed for 516 times, which showed
that CD_4^+ ≥200/μl in 278 times (53. 9% ) and CD_4^+<200/μl in 238 times (46. 1 % ); ② In all the patients with CD_4^+>200/μl, fit-
ness was found in 66 times (23.7% ), decrement of memory in 51 times (18. 3% ), loss of hair in 65 times (23.4% ), herpes zoster in
65 time (23. 3% ) and enlarged lymph nodes in 128 times (46. 3% ). In those patients with CD_4^+ <200/μl, fever was found in 228 times
(95. 8% ), diarrhea in 216 times (90. 8% ), oral candidiasis with oral ulcer in 192 times (80. 7% ), rash in 67 times (28. 2% ) and decre-
ment of body weight in 168 times (70. 7% ). Conclusions Clinical symptoms are less common in patients with CD_4^+≥200/μl and some-
times fitness, loss of hair, decrement of memory and lymph node enlargement appear. However, fever, diarrhea, oral candidiasis with
oral ulcer and decrement of body weight are very common in patients with CD_4^+ < 200/μl.
出处
《传染病信息》
2002年第4期166-168,共3页
Infectious Disease Information
