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IL-17与支气管哮喘 被引量：2

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摘要 白介素 17(IL 17)是由活化CD4 + 、CD4 5RO+ 记忆T细胞产生的一种细胞因子。IL 17在体外能激活支气管哮喘 (哮喘 )患者的成纤维细胞 (FB)、巨噬细胞产生并分泌一系列与气道重构有关的细胞因子 ,如GM CSF、TNF α、IL 1β等 ,还能与FB一起支持CD34+ 造血前体细胞增殖和分化成熟为中性粒细胞 ,是T细胞诱导的炎症反应的早期启动因素 ,可能参与哮喘的发病与气道重构。
作者 顾晓燕
机构地区 南京医科大学第一附属医院呼吸科
出处 《国外医学（呼吸系统分册）》 2002年第6期281-282,285,共3页 Section of Respiratory System Foreign Medical Sciences
关键词 生物学作用 IL-17 支气管哮喘 中性粒细胞
分类号 R562.25 [医药卫生—呼吸系统]
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参考文献28

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同被引文献36

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国外医学（呼吸系统分册）
2002年 第6期

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