1Robbins A, Spitz IM. Mifepristone: Clinical pharmacology[J].Clinical Obstetrics and Gynecology, 1996;39: 436
2Donaldson MS, Dorflinger L, Brown SS, eds. Clinical application of mifepristone RU486 and other antiprogestins[M].Washington DC:National Academy, 1993;1~277
3Horwitz KB. The molecular biology of RU486. Is there a role for antiprogestins in the treatment of breast cancer?[J].Endocrine Rev, 1992;13:146
4Sartorius CA, Groshong SD, Miller LA, et al. New T47D breast cancer cell lines for the independent study of progesterone B-and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonist by cAMP[J]. Cancer Res, 1994;54:3868
5Neulen J, Williams RF, Breckwoldt M, et al. Noncompetitive antioestrogenic actions of progesterone antagonists in primate endometrium: enhancement of estrogen and progesterone receptors with blockade of postreceptor proliferative mechanisms[J]. Hum Reprod, 1996;11:1533
6Murphy AA, Morales AJ, Kettel LM, et al. Regression of uterine leiomyomata to the antiprogesterone RU486: does-response effect[J].Fertil. Steril, 1995;,64:187
9Klijn JG, Setyono HB, Foekens JA. Progesterone antagonists and progesterone receptor modulators in the treatment of breast cancer[J].Steroids, 2000;65(10-11):825
10Alban P, Hurd C, Dinda S, et al. Differential regulation of retinoblastoma protein by hormonal and antihormonal agents in T47D breast cancer cells[J].J-Steroid-Biochem-Mol-Biol, 2001;77(2-3):135
6Zong WX,Li C,Hatzivassiliou G,et al. Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis[J] .J Cell Biol, 2003, 162 (1):59-69.
7Samuel T,Okada K,Hyer M,et al. clAP1 Localizes to the nuclear com- partment and modulates the cell cycle [ J]. Cancer Res, 2005,65:210 - 218.
8Kuo PL,Hsu YL,Kuo YC,et al. The anti-proliferative inhibition of el- lipticine in human breast mda-rob-231 cancer cells is through cell cycle arrest and apoptosis induction[J]. Anticancer Drugs,2005,16(7): 789 - 795.
9Nakshatri H, Rice SE, Bhat-Nakshatri P. Antitumor agent parthenolide reverses resistance of breast cancer ceils to tumor necrosis factor relat- ed apoptosis-inducing ligand through sustained activation of c-Jun N -terminal kinase[J]. Oncogene,2004,23 (44): 7 330 -7 344.
10Suzuki Y,Nakabayashi Y,Nakatak et al. X-linked inhibitor of apopto- sis protein (XIAP) inhibits caspase-3 and caspase-7 in distinct modes[J]. J Biol Chem,2001,76(29): 27 058 -27 063.