甲亢和甲亢已被控制患者骨密度的变化

The changes of bone density in patients with hyperthyroidism and controlled hyperthyroidism

作者用国产GMY-Ⅰ型骨密度仪测定109例正常人(A组),54例甲亢(B组)和68例甲亢已被控制(C组)患者右前臂远侧端1/3处桡、尺骨的骨密度(BD).结果表明,B组的BD值均低于A组(P<0.05或P<0.01),C组的BD值(30～39岁男性组除外)虽均高于B组,但在统计学上无差异(P>0.05),提示甲亢对BD有着重要影响,在甲亢被控制以后的短期内,其BD仅有部分程度的回升.结果还表明,C组男性的BD在50岁以前可随甲功恢复而有所回升;C组女性的BD在50岁以前并不能随甲功恢复而回升或程度很低,在50岁以后继续下降。

Bone densities (BD) of the radius and the ulna at 1/3 position of the distal end of the right arm in 109 normal subjecte (Group A), 54 patients with hyperthyroidism(Group B) and 68 patients with controlled hyperthyroidism (Group C) were examined with domestic-made bone density meter (model GMY-I). The findings indicated that the BD value of Group B was lower than that of Group A (P<0.05 -0.01); the BD value of Group C (except males with age ranging from 30 to 39), though higher than that of Group B, showed no statistical difference (P>0.05). The results revealed that hyperthyroidism exerted an important effect on bone density and bone density only partially recovered shortly after hyperthyroidism was controlled. The findings also demonstrated that BD might increase as the function of the thyroid gland regressed in males aged less than 50 in Group C and BD could not improve in females aged less than 50 in Group C and BD continued to decline after 50 years old.