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IL-1Ra,IL-1Ra基因多态性与溃疡性结肠炎 被引量：1

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摘要 IL - 1Ra,IL - 1Ra基因多态性与溃疡性结肠炎 (U C)的相关性研究是从遗传基因角度探讨了 UC的发病。通过对该方面深入研究可望进一步认识到 U C发病机制 。
作者 龙友明
机构地区 广东医学院附属医院消化内科
出处 《国外医学（遗传学分册）》 2002年第6期337-340,共4页 Foreign Medical Sciences(Section of Genetics )
关键词 溃疡性结肠炎 白细胞介素1 受体拮抗剂 IL-1RA 基因多态性 UC
分类号 R574.62 [医药卫生—消化系统]
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参考文献20

  • 1Daig R et al. Gut, 2000, 46:350-358.
  • 2Casini-Raggi V et al. J Immunol, 1995,154:2434-2440.
  • 3Tarlow JK et al. Hum Genet, 1993,91:403-404.
  • 4Mansfield JC et al. Gastroenterology, 1994,106:637-642.
  • 5Bioque G et al. Clin Exp Immnunol,1995,102:379-383.
  • 6Bioque G et al. Eur J Gastroenterol Hepatol, 1996,8:105-110.
  • 7Hacker UT et al. Gut,1997,40:623-627.
  • 8Hacker UT et al. Eur J Clin Invest, 1998,28:214-219.
  • 9Louis E et al. Gut,1996,39:705-710.
  • 10Heresbach D et al. Am J Gastroenterol,1997,92:1164-1169.

同被引文献18

  • 1Kuschner WG,D'Alessandro A,Wong H. Dose-dependent cigarette smoking-related inflammatory responses in healthy adults[J].European Respiratory Journal,1996,(10):1989-1994.
  • 2Zeidel A,Beilin B,Yardeni I. Immune response in asymptomatic smokers[J].Acta Anaesthesiologica Scandinavica,2002,(08):959-964.
  • 3Ouyang Y,Virasch N,Hao P. Suppression of human IL-1beta,IL-2,IFN-gamma,and TNF-alpha production by cigarette smoke extracts[J].Journal of Allergy and Clinical Immunology,2000,(02):280.
  • 4Masuda H,Nakamura Y,Tanaka T. Distinct relationship between HLA-DR genes and intractability of ulcerative colitis[J].American Journal of Gastroenterology,1994,(11):1957-1962.
  • 5Mansfield JC,Holden H,Tarlow jk. Novel genetic association between ulcerative colitis and the anti inflammatory cytokine interleukin 1 receptor antagonist[J].Gastroenterology,1994,(03):637-642.
  • 6Matri S,Karoui S,Filali A. Tobacco and inflammatory bowel disease[J].La Tunisie medicale,2000,(12):693-698.
  • 7Sher ME,Bank S,Greenberg R. The influence of cigarette smoking on cytokine levels in patients with inflammatory bowel disease[J].Inflammatory Bowel Diseases,1999,(02):73-78.
  • 8Ko JK,Sham NF,Guo X. Beneficial intervention of experimental colitis by passive cigarette smoking through the modulation of cytokines in rats[J].Journal of Investigative Medicine,2001,(01):21-29.doi:10.2310/6650.2001.34087.
  • 9Eliakim R,Reif S,Lavy A. Passive smoking in patients with inflammatory bowel disease:an Israeli multicentre case-control study[J].European Journal of Gastroenterology and Hepatology,2000,(09):975-979.
  • 10Guo X,Wang WP,Ko JK. Involvement of neutrophils and free radicals in the potentiating effects of passive cigarette smoking on inflammatory bowel disease in rats[J].Gastroenterology,1999,(04):884-892.

引证文献1

国外医学（遗传学分册）
2002年 第6期

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