胚胎干细胞的体外诱导分化

Differentiation of Embryonic Stem Cells in vitro

胚胎干细胞是从早期囊胚内细胞团或桑葚胚中分离的一种多潜能细胞,具有体外无限增殖和自我更新能力,而且还能被定向诱导分化形成机体几乎所有的细胞类型,如肝细胞、造血细胞、成骨细胞、神经细胞、神经胶质细胞、肌肉细胞、胰岛细胞、内皮细胞、黑色素细胞、淋巴细胞、脂肪细胞、成纤维细胞等。

Embryonic stem cells, derived from inner cell mass of early blastocysts or morula, are undifferentiated, immortal cells capable of proliferating and differentiating into derivatives of all three embryonic germ layers. A wide variety of cell types and tissues including lymphocytes, myocardium, lymphoid precursors, pancreatic islets, oligodendrocytes, myelinate, glial cells, neurons, hematopoietic cells, hepatic cells, chondrogenic cells, melanocytes, myocytes, crossstriated muscle, cartilage, epithelia were induced with embryonic stem cells.