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家蚕丝素蛋白对大鼠胆固醇代谢的影响 被引量:1

Effect of Silk Fibroin of the Silkworm (Bombyx mori L.) on Cholesterol Metabolism in the Rat
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摘要 研究了经酸解后制得的家蚕丝素蛋白氨基酸组成以及对高血脂实验鼠血清和肝脏内胆固醇及转氨酶的活性变化的影响。结果表明 :所得的家蚕丝素蛋白粉氨基酸组成丰富 ,其中甘氨酸、丙氨酸、丝氨酸和酪氨酸含量占全部氨基酸总量的 95 %;家蚕丝素蛋白能显著地降低血清胆固醇含量和谷草转氨酶及谷丙转氨酶活性 ,提高动物肝组织中的胆固醇浓度和谷丙转氨酶的活性。 In this paper,the amino acids composition in the silk fibroin (SF) treated by HCl acidolysis has been analyzed and the effect of SF on serum and liver cholesterol and transaminase (GPT & GOT) activities in rats loaded with cholesterol has been studied.The result showed that the silk fibroin (SF) contains rich amino acids and some amino acids such as Gly?Ala?Ser and Tyr are about 95% of total amino acids.SF decreases the serum cholesterol level and GOT & GPT activities significantly,and enhances the cholesterol concentration and GPT activity in the rat's liver.
出处 《蚕业科学》 CAS CSCD 2002年第4期301-303,共3页 ACTA SERICOLOGICA SINICA
基金 国家茧丝绸发展风险基金第三批资助课题
关键词 家蚕 丝素蛋白 大鼠 胆固醇代射 氨基酸组成 转氨酶 酶活性 Silk fibroin Cholesterol metabolism Rat
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