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新城疫病毒抗癌作用及其应用的研究进展 被引量：2

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摘要 新城疫病毒(Newcastle disease virus,NDV)为反义负链RNA病毒,能选择性的杀伤人类肿瘤细胞。应用NDV免疫肿瘤细胞进行各种体内外实验研究,均有不同程度的抗肿瘤效应。用NDV对癌症病人进行临床治疗则可延长肿瘤病人的存活期,肿瘤复发率较低。作用机制包括其直接对肿瘤细胞产生细胞毒作用;增强机体的各种细胞及体液免疫;诱导多种细胞因子的产生。其中T细胞的杀肿瘤作用增强及活化巨噬细胞数量增加是主要的抗瘤因素。
作者 刘开扬 刘芳
机构地区 张家口医学院微生物学教研室
出处 《中国肿瘤生物治疗杂志》 CAS CSCD 2002年第4期289-291,共3页 Chinese Journal of Cancer Biotherapy
基金 河北省教委基金(2002104)
关键词 新城疫病毒 抗癌 生物治疗
分类号 R730.54 [医药卫生—肿瘤]
  • 相关文献

参考文献19

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二级参考文献9

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共引文献9

同被引文献16

  • 1岳惠芬,刘名光,梁新强,崔英.新城疫病毒Ⅳ系活疫苗辅助治疗肿瘤的临床效果观察[J].广西医学,2005,27(11):1716-1719. 被引量：2
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二级引证文献7

中国肿瘤生物治疗杂志
2002年 第4期

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