自然人群血糖、体重指数、腰臀比与血压的关系

Association of blood glucose, body mass index and waist-hip ratio with blood pressure in the population

目的 探讨自然人群中血糖、体重指数 (BMI)、腰臀比 (WHR)的水平对血压的影响及作用的大小。方法 应用 1998年广东省糖尿病流行病学调查资料 ,采用分层整群抽样方法 ,调查对象年龄在 2 0～ 74岁。血糖值为早晨空腹口服 75g葡萄糖 2h后的血糖值。糖尿病及糖耐量低减(IGT)的诊断标准采用 1999年WHO糖尿病诊断标准。高血压诊断标准采用 1999年中国高血压防治指南。结果 共调查113 77人 ,其中男性 5 183人 ,女性 6194人 ,平均年龄 43岁 ,平均收缩压、舒张压、血糖、体重指数、腰臀比分别为117mmHg、74mmHg、10 4mg/dL、2 2kg/m2 和 0 84。糖尿病者高血压患病率明显高于血糖正常者 ,为 45 3 %比 14 4% ,糖耐量低减者高血压患病率明显高于糖耐量正常者 ,为3 2 2 %比 14 5 % ,肥胖者高血压患病率明显高于非肥胖者 ,为 2 1 5 %比 10 4%。多重线性回归模型分析显示 ,年龄、血糖、体重指数、腰臀比对男女性收缩压和舒张压有显著影响。结论 广东省自然人群的分析结果显示 ,血糖、体重指数和腰臀比是影响血压的重要因素 ,在控制我省高血压患病率不断增加的同时 ,尚须要注意控制血糖。

Objective To explore the impact of blood glucose, body mass index (BMI) and waist to hip ratio (WHR) on blood pressure (BP) in a nature population. Methods A stratified cluster sampling method was used according to the Diabetes Mellitus Epidemiology Survey Program in Guangdong in 1998. The age ranges of the participants were from 20 to 74 years old. A plasma glucose level 2 hr after 75 g oral glucose was measured in the morning. The diagnosis of diabetes mellitus and impaired glucose tolerance (IGT) were followed the WHO criteria in 1999. Criteria for the diagnosis of hypertension were according to the Chinese hypertension prevention and treatment guideline in 1999.Results A total of 11 377 participants were involved in the investigation, included 5 183 mem and 6 194 women. The mean age was 43 years old. The average of systolic and diastolic BP, blood glucose, BMI and WHR was 117 mmHg, 74 mmHg, 104 mg/dL, 22 kg/m 2 and 0 84 respectively. Prevalence of hypertension was significantly higher in diabetes mellitus than in people with normal blood glucose, 45 3% vs 14 4%. For IGT person prevalence rate of hypertension was significantly higher than people whose oral glucose tolerance test was normal, 32 2% vs 14 5%. The obesity person has significantly higher prevalence rate of hypertension than the normal weight person, 21 5% vs 10 4%. Multivariable regression analysis showed that age, blood glucose, BMI and WHR have obvious impact on both SBP and DBP for both men and women.Conclusions The analysis from Guangdong population showed that blood glucose, BMI and WHR are important factors for blood pressure. For preventing rapid increase of hypertension in the population, controlling blood glucose, BMI and WHR should pay more attention.