N-乙酰吗啉的合成研究

Study on the synthesis of N-acetyl morpholine

对以吗啉和醋酐为原料 ,在脱水剂的作用下合成N 乙酰吗啉进行了研究 .考察了原料配比、反应时间、加料方式、脱水剂用量等因素对N 乙酰吗啉合成的影响 ,采用真空蒸馏装置对产品进行精制 .在适宜工艺条件下 ,吗啉转化率达 98.5 2 % ,N 乙酰吗啉收率达 91 .0 6% .产品经精制 ,纯度达 98.67% .

N acetyl morpholine is synthesized with morpholine and acetic anhydride as raw materials.The effects of the ratio of raw materials,reaction time and the method of the reaction are researched.The product is distillated by a vacuum distillation.Under the suitable reaction conditions,the conversion of morpholine is 98.52% and the yield of N acetyl morpholine is 91.06%.The purity of product distillated is 98.67%.