缺氧性脑病16例报告

Anoxic encephalopathy: a report of sixteen cases

目的 探讨缺氧性脑病的临床特征。方法 回顾分析 16例缺氧性脑病的病因、主要临床表现、磁共振成像 (MRI)结果、治疗方法及疗效。结果 16例均有明确的脑缺氧病史。临床主要表现意识障碍、锥体外系症状、锥体束征、精神症状、智能减退及去皮层综合征 ,部分病人呈迟发性脑病表现。头颅MRI检查主要见两侧基底节区对称性异常信号 ,呈长T1长T2 改变。本组多数病人经对症、神经营养、改善脑循环、高压氧仓等治疗 ,脑受损症状基本消失或好转。结论 认识缺氧性脑病有助于该病得到及时合理的治疗 ;头颅MRI检查对缺氧性脑病有重要诊断价值。

Objective To study the clinical features of anoxic encephalopathy.Methods The etiological factors, main manifestations, results of brain magnetic resonance imaging(MRI) examination, treatments and effects in sixteen patients with anoxic encephalopathy were reviewed.Results All the sixteen cases had anoxic histories on brain. The main symptoms and signs were conscious disturbance, extrapyramidal symptom, pyramidal sign, psychiatric symptom, hypophrenia and decorticate syndrome. Some patients presented as delayed postanoxic encephalopathy. Brain MRI examinations showed that the abnormal signals were mainly located in the bilateral basal ganglia with long T 1 and long T 2 changes. After symptomatic, neurotrophic, cerebral circulation improvement treatments and hyperbaric oxygen therapy, the majority of these patients nearly recovered or improved.Conclusion Recognition of anoxic encephalopathy is important for promtly and appropriate management of such patients. MRI is one of the most important diagnostic methods for this disease.