摘要
目的 :提高对原发于鼻腔、鼻窦恶性黑色素瘤的诊疗水平。方法 :对本院 1992～ 2 0 0 0年收住的 19例鼻腔、鼻窦原发恶性黑色素瘤的临床表现、诊断、治疗方法和随访结果进行分析。结果 :该病病理与临床易与鼻息肉、鼻腔癌、血管瘤相混淆 ,彻底的手术切除及良好的局部控制与生存时间有关 ,放疗、化疗与免疫治疗的疗效有待进一步验证。结论 :鼻腔、鼻窦原发恶性黑色素瘤为临床难治疾病之一 ,预后较差 ,早期诊断及彻底手术切除是提高疗效的首选措施。
Objective:To investigate the treatment effect of malignant melanoma in nasal cavity and paranasal sinus.Methods:Nineteen patients with malignant melanoma in nasal cavity and paranasal sinus were treated by surgery in our department from 1992 to 2000.There were 11males and 8 females,ranging in age from 31 to 69 years old.Among 19 cases,tumors located nasal septum 5,turbinate 1 ,maxillary sinus 1,ethmoid sinus 8,maxillary and ethmoid sinus 3,and sphenoid sinus 1.All 19 cases were diagnosed by pathology(Harwood one stage).Surgical treatment was completed in all 19 patients.Result:The rate of follow\|up was 78 9%(15/19),13 cases died in 2 months to 4 years, survival 2 cases were one year treated.Conclusion:The malignant melanoma of nasal cavity and paranasal sinus was one of refractory diseases.Poor prognosis was noted in this disease.Early diagnosis and extensive excision should be to better prognosis.
出处
《耳鼻咽喉（头颈外科）》
2002年第6期332-334,共3页
Chinese Arch Otolaryngology-Head Neck Surg
