母乳超氧化物歧化酶的动态测定及其临床意义

The Clinic Significance and Dynamic Changes of the Superoxide Dismutase in Human Milk

【目的】 探讨不同哺乳期母乳超氧化物歧化酶 (SOD)活性的变化规律及其临床意义。 【方法】 测定和分析 3 0例健康母亲初乳、过渡乳和成熟乳中SOD活性的变化规律。 【结果】 随着哺乳时间的延长 ,母乳中SOD活性逐渐降低 (65 .91± 2 5 .2 1) μU /ml,(63 .42± 15 .2 8) μU/ml和 (5 2 .0 7± 2 0 .2 2 ) μU/ml ,F =7.982 4,P <0 .0 5 )。初乳和过渡乳SOD的活性显著高于成熟乳 (Q =5 .763 6,P <0 .0 1和Q =4.0 973 ,P <0 .0 1)。 【结论】 不同哺乳期母乳中SOD活性的变化规律与婴儿的生长发育相适应 ,初乳和过渡乳中高活性的SOD对保障新生儿的营养和健康有十分重要的意义 ,对于婴儿要强调和鼓励母乳喂养。

To study the dynamic changes in the activity of superoxide dismutase(SOD) of human milk at different periods of lactation.A totaly of 30 healthy women aged 21-28 years old were sampled and the activity of SOD of human milk were measured.The activity of SOD of human milk at different periods of lactation showed significant difference(65.91±25.2)nU/ml,(63.42±15.28)nU/ml and (52.07±20.22)nU/ml,F=7.9824,P<0.05).The activity of SOD of colostrum and transitional milk were significantly higer than that of mature milk(Q=5.7636,P<0.01 and q=4.0973,P<0.01) respectively.[Conclusion]The dynamic changes in the activity of SOD human milk is fit for the growth and development and healthy of infants.Breast feeding should be emphasized and encouraged for infants.