摘要
Utilizing aldol condensation and β-elimination as the key steps, butenolidesⅠ and Ⅱ in excellent enantiomeric purity have been concisely synthesized for the first time.According to the rotation difference between synthetic samples and natural products, the rotationswere corrected by the calculation upon HPLC measurements. In addition, an efficient way tosynthesize methyl pentadec-14-enoate was developed.
Utilizing aldol condensation and β-elimination as the key steps, butenolidesⅠ and Ⅱ in excellent enantiomeric purity have been concisely synthesized for the first time.According to the rotation difference between synthetic samples and natural products, the rotationswere corrected by the calculation upon HPLC measurements. In addition, an efficient way tosynthesize methyl pentadec-14-enoate was developed.
基金
ProjectsupportedbytheMajorStateBasicResearchDevelopmentProgramofChina (No .G2 0 0 0 0 775 0 0 )
theNationalNaturalScienceFoundationofChina (No.2 9790 12 6 )
ChineseAcademyofSciences
andShanghaiMunicipalCommissionofScienceandTechnology
