摘要
Crystals of the chiral malic acid hydrate (C_4H_6O_5·H_2O) were unexpectedlyobtained from an ethanol/water solution containing racemic D, L-malic acid and L-asparagine. Thecrystal belongs to orthorhombic space group P2_12_12_1 with cell dimensions of a = 0.5576(1), b =0.9818(2), c = 1.1793(2) nm, V = 0.6455(2) nm^3, Z = 4, μ(Mo K_a) =0.152 mm^(-1), F(000) = 320, D_c= 1.565 g·cm^(-3), R=0.051, wR = 0.136 for 657 observed reflections [ I > 2σ(I) ]. Thesignificant difference in bond distances for carboxyl groups suggests that the crystal consist ofmalate anion and protonized crystalline water. This is a report for direct separation of racemicmixture, i.e., without the formation of a molecular complex of raceme with a chiral separatingreagent.
Crystals of the chiral malic acid hydrate (C_4H_6O_5·H_2O) were unexpectedlyobtained from an ethanol/water solution containing racemic D, L-malic acid and L-asparagine. Thecrystal belongs to orthorhombic space group P2_12_12_1 with cell dimensions of a = 0.5576(1), b =0.9818(2), c = 1.1793(2) nm, V = 0.6455(2) nm^3, Z = 4, μ(Mo K_a) =0.152 mm^(-1), F(000) = 320, D_c= 1.565 g·cm^(-3), R=0.051, wR = 0.136 for 657 observed reflections [ I > 2σ(I) ]. Thesignificant difference in bond distances for carboxyl groups suggests that the crystal consist ofmalate anion and protonized crystalline water. This is a report for direct separation of racemicmixture, i.e., without the formation of a molecular complex of raceme with a chiral separatingreagent.
基金
theNationalNaturalScienceFoundationofChina (No.2 99730 36 )
