摘要
With the xanthan synthesis in Xanthomonas campestris as an example, two methods for metabolicflux analysis of overdetermined system, the experimental data error minimization method and the equation errorminimization method, are compared from their mathematical basis, rationality of the results and the easiness ofcomputation. The results show that the experimental data error minimization method is appropriate in metabolicflux analysis of overdetermined system.
With the xanthan synthesis in Xanthomoaas campestris as an example, two methods for metabolic flux analysis of overdetermined system, the experimental data error minimization method and the equation error minimization method, are compared from their mathematical basis, rationality of the results and the easiness of computation. The results show that the experimental data error minimization method is appropriate in metabolic flux analysis of overdetermined system.
基金
Supported by the National Natural Science Foundation of China (No. 20036010), the National Science Fund for Distinguished Young Scholars (No. 20028607) and the Doctorate Foundation of MOE (No. 20000005622).
