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A Convenient Synthesis of the Substituted 2,3-Diarylindole the Potent Selective COX-2 Inhibitors

A Convenient Synthesis of the Substituted 2,3-Diarylindole the Potent Selective COX-2 Inhibitors
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摘要 Phenyl sulfone-containing 2, 3-diarylindole derivatives were designed and identified to be selective COX-2 inhibitors. A convenient synthetic route was also developed for the synthesis of the novel inhibitors. Phenyl sulfone-containing 2, 3-diarylindole derivatives were designed and identified to be selective COX-2 inhibitors. A convenient synthetic route was also developed for the synthesis of the novel inhibitors.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2002年第4期296-298,共3页 中国化学快报(英文版)
基金 support for this study was provided by the National Natural Science foundation of China.
关键词 Nonsteroidal anti-inflammatory drugs (NSAIDs) selective COX-2 inhibitors substituted 2 3-diarylindole pharmacophore. Nonsteroidal anti-inflammatory drugs (NSAIDs), selective COX-2 inhibitors, substituted 2, 3-diarylindole, pharmacophore.
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