摘要
以大鼠力竭性运动为模型,观察了牛磺酸对力竭运动时大鼠白肌线粒体脂质过氧化、抗氧化系统及总Ca2+浓度的影响.结果显示:牛磺酸可降低大鼠力竭运动后白肌线粒体脂质过氧化水平,提高大鼠力竭运动后白肌线粒体超氧化物歧化酶(SOD)的活性,保持大鼠力竭运动后白肌线粒体还原性谷胱甘肽含量及总Ca2+浓度.结果提示牛磺酸可减少力竭运动后因脂质过氧化而产生的自由基,降低自由基对白肌线粒体的攻击,维持线粒体膜的功能,说明牛磺酸有保护白肌线粒体的功能和防止白肌线粒体功能损伤的作用.
Taking incremental exercise to exhaustion, the authors measured MDA content SOD activity GSH content and Total calcium concentration of the fast muscular mitochondria in rats at rest, immediately after exhaustive having supplied with 1% taurine in drinking water during four weeks of not. The results showed that taurine supplement decreased the lipid peroxidation level and increased SOD activities, GSH content and total calcium concentration significantly in the fast muscular mitochondria of rats after exhaustive exercise. These findings suggested that taurine could decrease free radicals, and thus protect the damage of fast muscular mitochondria from the lipid peroxidation after exhaustive exercise and retain the function of the fast muscular mitochondria.
出处
《湖南师范大学自然科学学报》
EI
CAS
北大核心
2002年第4期73-75,共3页
Journal of Natural Science of Hunan Normal University
基金
广东省教育厅自然科学重点科研项目
