复方皂矾丸与放化疗同步用药的临床研究

Clinical Research of Effect of Pill Fufang Zaofan Together with Radiotherapy and Chemotherapy

目的:研究复方皂矾丸与化疗、放疗同步应用,对恶性肿瘤患者的骨髓保护作用。方法:化疗治疗组包括57例恶性肿瘤患者,化疗前1周起,服用复方皂矾丸,直至化疗结束后1周。化疗对照组28例,不服用复方皂矾丸。从治疗前开始监测病人的血常规,直至治疗开始后4周。放疗治疗组有43例恶性肿瘤患者,服用复方皂矾丸;对照组25例,不服用复方皂矾丸,血象监测方法与化疗组相同。结果:服用复方皂矾丸的治疗组的白细胞平均数显著高于对照组,治疗组放化疔后白细胞低于正常的例数明显少于对照组,4周内化疗治疗组和放疗治疗组白细胞正常率明显高于对照组。结论:复方皂矾丸与化疗、放疗同步应用,能够保护恶性肿瘤患者的骨髓免受化疗、放疗的损伤,提高患者对放化疗的耐受性。

Objective: To study effect of Pill Fufang Zaofan together with radiotherapy and chemotherapy at same time.Methods: Treat group administrated Pill Fufang Zaofan from 1 week before radiotherapy and chemotherapy, to 4 weeks after radiotherapy and chemotherapy. Control group didn't administrate Pill Fufang Zaofan.Other agents of two groups are no difference.Results; White blood cells (WBC) of treat group were much more than those of control group. The cases of treat group in which WBC was lower than normal level were obviously less than those of control group. Conclusion: Pill Fufang Zaofan can protect bone marrow when using with radiotherapy and chemotherapy at same time.