环磷腺苷葡胺、维拉帕米和硫酸镁三联转复心房颤动

Huanlinxiangpuan,verapamil and magnesium sulfate revert atrial fibrillation

目的 观察环磷腺苷葡胺、维拉帕米和硫酸镁三联疗法对持续性或慢性心房颤动 (房颤 )的转复作用及转复半年后窦律维持率。方法 治疗组静滴环磷腺苷葡胺、硫酸镁 ,静注或口服维拉帕米 ;对照组除心室率快及伴有心衰者静注毛花苷C外 ,其余均用安慰剂。结果 治疗组 34例转复率 73 5 3% ,对照组 34例转复率 8 8% ,两组比较差异有显著意义 (P <0 0 0 1)。治疗组总转复率达 72 3% ,半年窦律维持率 6 3 83%。结论 环磷腺苷葡胺、维拉帕米和硫酸镁三联疗法转复持续性或慢性房颤安全有效 ,半年窦律维持率亦较高。

Objective To observe the effecacy of huanlinxianganpuan,verapamil,magnesium sulfate triadic therapy on persistant or chronic atrial fibrillation,and observe the maintenance rate of sinus rhythm.Methods Huanlinxianganpuan and magenesium sulfate were intravenous infused and verapamil was intravenously injected or oraly administered.In control group the patients were given placebo except for those accompanied with rapid ventricular rate or heart failure.Results In treating group the reverting ratio was 73.53% in 34 patients and it was 8.8% in control group.There was significant difference(P<0.001).The total reverting rate in treating group was 72.3%.Sinus rhythm maintenence ratio for half a year was 63.83%.Conclusion Huanlinxianganpuan,verapamil and magnesium sulfate triadic therapy is effective and safety for reverting persistant or chronic atrial fibrillation,maintenance ratio for half a year is quite higher.