原发性高血压及伴非胰岛素依赖性糖尿病的心率变异性分析

HEART RATE VARIABILITY IN PATIENTS WITH ESSENTIAL HYPERTENSION AND NON- INSULIN - DEPENDENT DIABETES MELLITUS

目的:探讨原发性高血压(EH)与原发性高血压伴非胰岛素依赖性糖尿病(EH+NIDDM)心率变异性的异同。方法:健康体检者32例作为对照组,EH病人57例为EH组,另一组17例为EH+NIDDM组,记录24h动态心电图,进行HRV分析。结果:EH组及EH+NIDDM组SDNN、SDANN、rMSSD、高频功率显著低于对照组,p<0.05,低频功率、低频与高频功率之比,EH组显著高于对照组,p<0.05,EH+NIDDM组SDNN、低频功率、低频与调频功率比值显著低于EH组,p<0.05。结论:EH+NIDDM患者较单纯EH者自主神经功能损害更明显。

Objective:To compare the differences of heart rate variability (HRV)in patients with essential hypertension(EH)and with EH and non - insulin - dependent diabetes mellitus(EH + NIDDM) .Method: HRV on 24 - hour electrocardiograms was examined in 32 healthy subjects (control group),57 patients with EH alone(EH group)and 17 ones with EH+ NIDDM (EH+ NIDDM group).Result: SDNN, SDANN.rMSSD, high frequency reduced significandy in EH and EH + NIDDM groups(p< 0.05) .The low frequency, ratio of low frequency to high frequency in EH group were higher than those of the control(P< 0.05) .SDNN, low frequency, ratio of low frequency to high frequency in EH + NIDDM group were significandy lower than those in EH group(p < 0.05). Conclusion: It is indicated that the autonomic nerve functional damage in EH + NIDMDM group is more severe than that in EH group.