尿氟在地方性氟中毒防治中的意义

The significance of urinary fluoride content on the endemic fluorosis

尿氟指标常常应用于地方性氟中毒的防治和监测工作中 ,尿氟含量可以反映环境氟暴露水平和人体氟摄入状况。个体尿氟变异较大 ,对于氟中毒的诊断价值不大 ;而群体尿氟在氟中毒病区与非病区之间以及不同程度病区之间往往有显著性差异 ,可以作为地方性氟中毒病区判定及防治效果评价的一个有意义指标 ,在地氟病防治工作中应研制基于人群水平的尿氟正常值。

Urinary fluoride was frequently applied to the endemic fluorosis control and surveillance, It was known that urinary fluoride content reflected the levels of environmental fluoride exposure and the condition of human fluoride intake. Urinary fluoride of individuals varied so largely that it was not proper for the disease diagnosis. Urinary fluoride of the population, however, demonstrated significantly difference between fluorosis areas and no-fluorosis areas or between the different severity fluorosis areas. It can be regarded as a significant index for the judgment of an endemic fluorosis areas and the assessment of the control effect, so the reference value for urinary fluoride should be formulated on the base of the population.