宫腔镜检对子宫内膜癌细胞播散及生存预后的影响

Effect of hysteroscopy on the dissemination and prognosis of endometrial cancer

目的评价宫腔镜检对子宫内膜癌细胞播散及生存预后的影响。方法回顾性分析我院2000年-2003年无宫外转移的子宫内膜癌患者105例,分为术前单纯性诊刮术组68例,宫腔镜检下诊刮术组37例,所有病例均行手术治疗,术中均取腹腔冲洗液找癌细胞。比较两组癌细胞腹腔内播散率及3年内复发率。结果单纯诊刮术组子宫内膜癌细胞腔内播散5例,发生率5/68(7.35%),宫腔镜检下诊刮术组子宫内膜癌细胞腹腔内播散3例,发生率3/37(8.11%),两组比较P>0.05,差异无统计学意义。单纯诊刮术组术后3年内复发4例,复发率4/68(5.88%),宫腔镜检下诊刮术组术后3年内复发3例,复发率3/37(8.11%),两组比较P>0.05,差异无统计学意义。结论宫腔镜检不增加子宫内膜癌细胞腹腔内的播散的风险,也不影响患者近期的生存预后。

Objectives To evaluate the influence of hysteroscopy on the dissemination and prognosis of endometrial cancer. Methods 105 cases of endometrial cancer without extrauterine dissemination and hospitalized in our hospital in 2000-2003 were analyzed retrospectively. All the patitents were divided into two groups,one group was the 68 patients performed diagnostic curettage only before operation,and the other group was the patients performed diagnostic curettage and hysteroscopy at the same time before operation. All the patients were treated with operation and performed peritoneal lavage during the operation to find cancer cell. The dissemination rates of peritoneal cavity and recurrence rates in three years were compared between two groups. Results There were 5patients with peritoneal cavity dissemination at the group performed diagnostic curettage only before operation,the dissemination rate was 7.35%(5/68),and 3 patients with peritoneal cavity dissemination at the other group performed diagnostic curettage and hysteroscopy at the same time before operation,the dissemination rate was 8.11%(3/37). There was no significant difference(P>0.05) between the two groups. There were 4 recurrences in the first group,the recurrence rate was 5.88%(4/68),3 recurrences in the second group,the recurrence rate was 8.11%(3/37). There was no significant difference(P>0.05) between the two groups. Conclusion The hysteroscopy do not influence its prognosis.