Framingham血管危险因素对认知储备的影响

Effect of Framingham Risk Factors on Cognitive Reserve

目的:探讨Framingham血管危险因素对老年人群认知储备是否存在损害作用。方法:纳入58例无卒中事件及痴呆的受试者进行Framingham十年心血管事件风险评估,将受试者分成低危、中危及高危组,比较三组间认知储备的差异。结果:58例受试者中低危组22例,中危组17例,高危组19例,三组间在年龄、教育年限及认知储备复合分数之间无统计学差异,但低危组较中危组、高危组的智商更高,且差异具有统计学意义。结论:Framingham血管危险因素对认知储备有损害作用。

Objective:To investigate the influence of Framingham risk factors on cognitive reserve(CR).Methods:Fifty-eight subjects without stroke and demention were recruitmented.All subjects were divided into three groups:low-risk group,moderate-risk group and high-risk group,which was depending on 10-year risk of total cardiovascular disease.Then three groups were compared on the cognitive reserve.Results:There were twenty-two subjects in low-risk group,seventeen subjects in moderate-risk group and nineteen subjects in high-risk group.There were no statistical differences between age,education and CRI complex scores.But the intelligence quotient(IQ)in low-risk group was higher than in moderate-risk group and high-risk group.Conclusion:Framingham risk factors had negative effects on CR.