摘要
干性年龄相关性黄斑变性占年龄相关性黄斑变性(AMD)的近90%,是导致老年人致盲的主要原因,但目前暂没有公认的干性AMD的治疗措施。本文针对近年来干性AMD的临床治疗方式进行综述。其中,自噬及线粒体靶向治疗值得关注,无疑为干性AMD的治疗提供了新方向。
Dry age-related macular degeneration(AMD)accounts for nearly 90% of AMD,which is main cause of blindness in the elderly,however,there is currently no FDA-approved treatment for dry AMD.This article reviews the progress of clinical treatment of dry AMD in recent years.Autophagy and mitochondrial targeted therapies are more worthy of attention,as it is undoubtedly to provide a new direction for the treatment of dry-related macular degeneration.
出处
《武汉大学学报(医学版)》
CAS
2018年第6期941-944,共4页
Medical Journal of Wuhan University
关键词
干性老年性黄斑变性
靶向治疗
自噬
线粒体基因
Dry Age-Related Macular Degeneration
Targeted Therapy
Autophagy
Mitochondrial Genes