硼替佐米治疗γ/δT细胞淋巴瘤白血病1例并文献复习

Bortezomib treatment on gamma/deltaT cell leukemia:a case report and literature review

目的:评估硼替佐米治疗γ/δT细胞淋巴瘤的效果。方法:分析总结1例γ/δT细胞淋巴瘤白血病的临床资料,并结合文献,对此疾病的特征及诊治情况进行分析。结果:γ/δT细胞淋巴瘤白血病是少见血液病,临床表现危重,死亡率高,目前治疗效果不佳。采用硼替佐米可以缓解临床症状。结论:针对γ/δT细胞淋巴瘤白血病,硼替佐米可以发挥良好的抗肿瘤作用。

Objective:To evaluate the efficacy of bortezomib in the treatment ofγ/δT cell lymphoma.Methods:The clinical data of one case ofγ/δT cell lymphoma leukemia were analyzed and the characteristics of this disease were analyzed in combination with the literature.Results:γ/δT cell leukemia is a rare hematological disease with severe clinical manifestations and high mortality.Bortezomib was effective to relieve the symptoms.Conclusion:Bortezomib have shown promise in the treatment ofγ/δT lymphoma leukemia as antineoplastic agents.