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骨髓瘤脊柱病变的外科手术治疗

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摘要 目的探讨骨髓瘤脊柱病变的外科手术治疗的指征、术式及并发症,明确术后疗效。方法回顾性分析自接受手术治疗的脊柱病变为主的30例骨髓瘤患者资料,根据患者的年龄、身体状况及病变部位情况,分别行微创手术(经皮椎体成形术/经皮椎体后凸成形术)、开放性手术(前路、后路或前后联合入路),术后全部转血液科后续治疗。手术前后分别对患者疼痛症状(VAS)、神经功能状态(Frankel)、生活质量(Karnofsky)、脊柱不稳定性情况进行对比分析。结果 30例患者术后随访4~36个月,平均随访25.8个月。术后患者疼痛症状、神经功能状态、生活质量均有明显改善(P<0.01),脊柱不稳定情况较术前明显改善并且随访期间未曾发生脊柱不稳定情况。结论对于有严重脊柱区疼痛或有神经功能损害或可能发展为脊柱不稳、已经脊柱不稳的骨髓瘤患者,外科手术治疗具有较高的症状缓解率和较低的并发症发生率。
出处 《河北医药》 CAS 2016年第18期2805-2807,共3页 Hebei Medical Journal
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