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新型2'-溴-2-羟基联苯类化合物的合成 被引量：2

Synthesis of Novel 2'-Bromo-biphenyl-2-ol Compounds
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摘要 以Pd(PPh3)4为催化剂,Na2CO3为碱,反应温度为90℃,在甲苯/乙醇/水混合溶剂中实现了邻二溴苯类化合物与邻羟基苯硼酸类化合物的Suzuki偶联反应,合成了9个2'-溴-2-羟基联苯类化合物(3a^3i),其中3b^3i为新化合物,其结构经1H NMR,13C NMR和ESI-MS表征。 A series of 2'-bromo-biphenyl-2-ol compounds( 3a ~ 3i) were synthesized by Suzuki coupling reaction of 2-hydroxyphenylboronic acid compounds with dibromobenzen compounds at 90 ℃ in the mixtures of toluene / ethanol / water,using Pd( PPh3)4as the catalyst and Na2CO3 as the base. 3b ~ 3i were new compounds. The structures were characterized by1 H NMR,13 C NMR and ESI-MS.
作者 吴海建 孙小强 王治明
机构地区 常州大学石油化工学院
出处 《合成化学》 CAS CSCD 2016年第1期47-50,58,共5页 Chinese Journal of Synthetic Chemistry
基金 国家自然科学基金项目资助(21372033) 江苏省高校自然科学研究重大项目资助(12KJA150002 14KJA150002)
关键词 双官能团 2’-溴-2-羟基联苯 SUZUKI偶联反应 钯催化 合成 difunctional group 2'-bromo-biphenyl-2-ol Suzuki coupling reaction palladium-catalysis synthesis
分类号 O625 [理学—有机化学]
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参考文献16

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二级参考文献37

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合成化学
2016年 第1期

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