新型四阳离子型1,2,3-三唑鎓环蕃的合成

Synthesis of A Novel Tetracationic 1,2,3-Triazolium Cyclophane

以间苯二酚为原料,经5步反应制得中间体4,4'-[4,6-双(己氧基)-1,3亚苯基]双{1-[4-(叠氮甲基)苯基]-1H-1,2,3-三氮唑}(6);6与1,5-二乙炔基-1,4-二(己氧基)苯在高度稀释的条件下经Click反应环合制得1,2,3-三唑环蕃(7);7与三甲基氧鎓四氟硼酸盐反应合成了全甲基化的新型1,2,3-三唑鎓环蕃,其结构经1H NMR,13C NMR和HR-ESI-MS表征。

An intermediate,4,4'-[4,6-bis( hexyloxy)-1,3-phenylene]bis{1-[4-( azidomethyl) benzyl]-1H-1,2,3-triazole}(6),was prepared by a five-step reaction from resorcinol. 1,2,3-Triazolophane( 7) was obtained by Click reaction of 6 with 1,5-diethynyl-2,4-bis( hexyloxy) benzene under pseudo-high dilution conditions. A novel tetramethylated 1,2,3-triazolium-phane was synthesized by the reaction of trimethyloxonium tetrafluoroborate with 7. The structure was characterized by1 H NMR,13 C NMR and HR-ESI-MS.