摘要
以邻苯二胺和香草醛为原料,合成了3个新型的香草醛缩苯并咪唑Schiff碱(5a^5c),其结构经1H NMR和IR表征。用菌丝生长速率法研究了5a^5c对小麦赤霉病菌(F.gra),马铃薯干腐病菌(F.oxy),玉米弯苞叶斑病菌(C.sor),番茄早疫病菌(A.sol)和棉花枯萎病菌(F.oxy.s.v)的抑制活性。结果表明:香草醛缩2-甲基-5-氨基苯并咪唑(5c)对F.gra,F.oxy和C.sor的抑制活性高于多菌灵,其EC50值分别为19.76 mg·L^(-1),24.94 mg·L^(-1)和29.15 mg·L^(-1)。
Three novel vanillin benzimidazole Schiff bases(5a ~ 5c) were synthesized,using o-phenylenediamine and vanillin as raw materials. The structures were characterized by1 H NMR and IR. The antibacterial activities of 5a ~ 5c against Fusarium oxysporium( F. oxy),Alternaria solani( A. sol),Fusarium graminearum( F. gra),Cercospora sorghi( C. sor) and Fusaurium oxysporiumf. sp. vasinfectum(F. oxy) were investigated by mycelial growth rate method. The results indicated that 5c exhibited better antimicrobial activities against F. gra,F. ox and C. sor than Carbendazim with EC50 of 19. 76 mg·L(-1),24. 94 mg·L^(-1) and 29. 15 mg·L^(-1).
出处
《合成化学》
CAS
CSCD
2016年第2期148-151,共4页
Chinese Journal of Synthetic Chemistry
基金
广西高校科学技术研究项目[KY2015LX304]
玉林师范学院科学研究项目[2014YJYB07]
关键词
苯并咪唑
希夫碱
合成
抑菌活性
benzimidazole
Schiff base
synthesis
antibacterial activity
